Psychological Variables Associated With Health-Related Quality-of-Life in Uruguayan Women Surgically Intervened for Breast Cancer

Micaela Reich, Eduardo Remor


Aim: This study described demographic, clinical, psychological and health-related quality of life (HRQOL) characteristics in women surgically intervened for breast cancer, and the present study was conducted to examine the association between these characteristics. Method: Uruguayan women (N = 116) diagnosed and surgically intervened for breast cancer were assessed on demographic, clinical and psychological indicators and HRQOL, by self-report questionnaires (i.e., BDI-II, PSS, Brief-COPE, and SF-36). Study was conducted adopting a non-experimental, cross-sectional methodology. After studying associations between variables assessed, hierarchical regression analyses were performed to identify HRQOL predictors. Results: HRQOL Physical Health Component (SF-36) was predicted by perceived stress and depression, above and beyond demographic and clinical factors. And HRQOL Mental Health Component (SF-36) was predicted by education, time elapsed since diagnosis of breast cancer, time hospitalized during the past year, perceived stress and depression. Conclusion: Results suggest that psychological variables may have a significant role for HRQOL prediction, and need to be taken into account along with demographic and clinical markers in order to explain HRQOL outcomes in women with breast cancer.


breast cancer; women; HRQOL; stress; depression; coping